Which NOACS are riskiest for gastrointestinal bleeding?

It is well-known that all new oral anticoagulants increase the risk of gastrointestinal bleeding (GIB), but new research shows some are more problematic than others.

Gastrointestinal bleeding (GIB) risks are lower with apixaban than with dabigatran or rivaroxaban,the results show.

These differences are significant, say the US researchers,  who looked at three matched-pair cohorts created from 372,380 patients with non-valve atrial fibrillation. Participants were exposed to dabigatran, rivaroxaban, or apixaban over a four and a half-year