Why older aspirin users need PPIs

Elderly patients taking daily aspirin after a stroke or heart attack should be given PPIs to reduce the risk of bleeding.

This is the conclusion of a Lancet study of 3166 patients, which found the risk of internal bleeding is far higher than was previously thought.

Compared with younger patients, older aspirin users were 10 times more likely to experience disabling or fatal gastrointestinal bleeding, the research shows.

The proportion of study participants suffering bleeds that required hospital admission rose from 1.5% a year for those under 65 to 3