A woman with chest pain

A 48-YEAR-OLD female presents with a history of a few weeks of chest pain walking uphill, with associated shortness of breath. The pain is worse if she continues to exercise and resolves when she stops. She has had no pain at rest.

She has a background of type 2 diabetes, previous hypertension (not requiring medication), and she quit smoking two weeks ago, previously smoking 20 cigarettes a day. Her last total cholesterol was 5.4, TG 2.0, LDL 3.4. She has no family history of premature ischaemic heart disease and no other significant past medical history.

On examination she was found to have

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