Yo-yo dieting linked to increased risk of CVD events

Study shows large fluctuations in metabolic parameters increase risk of death, MI and stroke

People who experience fluctuations in their weight, blood pressure, cholesterol and blood sugar are more likely to have MIs and strokes than those with stable measurements, a Korean study suggests.

The study analysed data from the Korean National Health Insurance System between 2005 and 2012 on more than 6.7 million people without a history of MI, diabetes, hypertension or high cholesterol.

All participants had at least three health examinations during the study period and the researchers followed half of them for more than 5.5 years.

They reported almost 55,000 deaths, more than 22,000 strokes and more than 21,000 heart attacks during the follow-up period.

Large fluctuations in metabolic risk factors of more than 5% — whether improvements or setbacks — were associated with a higher risk of death, according to the study in Circulation.