Avoid synthetic testosterone for replacement therapy: expert

Natural testosterone should be used in preference to synthetic androgens when hormone replacement is required, according to one of Australia’s leading endocrinologists.

Professor John Funder of the Prince Henry’s Institute, Melbourne, says men treated with synthetic ‘pure’ testosterone products miss out on the oestrogenic effects of the natural testosterone metabolite oestradiol on bone, cartilage and sexual functioning.

Writing in the Asian Journal of Andrology, Professor Funder says that unlike natural testosterone,