Conflicting results on bronchiolitis treatment

An answer on whether nebulised hypertonic saline is of benefit in children with bronchiolitis appears to be further away than ever as two US trials have produced contradictory results.

One randomised controlled trial published in JAMA Pediatrics this week showed that hypertonic saline given to children with bronchiolitis in the emergency department reduced hospital admissions. However, another RCT in the same journal found that infants with bronchiolitis and persistent respiratory distress n the ED had less improvement when given hypertonic saline compared with those who were given normal saline.