Grape seed protects bowel from chemo mucositis

Viticulturists may have the key to protecting the bowel from adverse effects of chemotherapy, with a study showing that grape seed extract ameliorates the intestinal mucositis caused by 5-fluorouracil.

South Australian researchers say an antioxidant and anti-inflammatory component of grape seed extract tannins, the procyanidins, is likely responsible for decreasing the histological damage caused by chemotherapy in the jejunum.

In an animal model Dr Amy Cheah and colleagues from the University of Adelaide showed that pre-treatment with grape seed extract prevented chemotherapy-induced