Premature consent?

Research involving children is a delicate area, so allegations that parents may not have been appraised properly of the risks involved in enrolling their very premature offspring in a randomised trial are bound to spark emotive reactions.

The Neonatal Oxygenation Prospective Meta-analysis (NeOProM) Collaboration, which included the BOOST II trial in Australia, is becoming a touchstone for concerns about ethical research, although debate has been largely confined to the pages of academic journals.

In one corner, investigators argue too

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