Abnormal lipids lead to insulin sooner

The study of 5250 patients showed faster progression of diabetes was associated with younger age at diagnosis, higher baseline triglyceride concentrations and lower HDL concentrations.

The study also showed that progression to needing insulin was also associated with low and high BMI, whereby the lowest risk of progression was the group with a BMI between 24 and 26.

While younger age at diagnosis and an earlier year of diagnosis were both independently associated with a faster progression, genetic