ACE inhibitor link to slower cognitive decline in dementia

The study, from University College Cork, in 361 patients with Alzheimer’s disease, vascular or mixed dementia, showed those taking centrally-acting ACE inhibitors such as ramipril had slower declines in cognitive function.

Scores on the standard mini-mental state examination improved by 1.2 points in the first six months in patients with dementia newly prescribed ACE inhibitors.

This compared with a 0.8 point decline in the group already taking ACE inhibitors and a one point decline in the group not taking them.

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