Acute pancreatitis linked to HRT in postmenopausal

Drawing on data from the population-based study in Sweden, researchers found ever-users of HRT had a nearly 60% increased risk of developing acute pancreatitis compared to never-users of the therapy.

Use of systemic therapy and longer duration of therapy (more than 10 years) further increased the risk.

Use of HRT may elevate triglycerides, which have been associated with increased risk of acute pancreatitis, and there was also some evidence exogenous oestrogen has deleterious effects on the pancreas, the researchers said.