AF patients on NOACs have higher stroke rate, study finds

Phasing out warfarin use among patients with arrhythmia may be contraindicated

Patients with atrial fibrillation (AF) taking non-vitamin K antagonist oral anticoagulants (NOACs) may be at a higher risk of ischaemic stroke than those on warfarin, a large study suggests.

Stroke

Although at odds with previous research, the results suggest a need for more intensive monitoring of levels of anticoagulation among patients taking NOACS, the authors said.

The retrospective US study compared relative stroke incidence among 71,300 patients with AF on a NOAC and 59,500 patients with AF on warfarin. Their records were held by a national hospital network database.

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