Alertness urged on hyperemesis gravidarum
Swedish researchers analysed a medical birth register of more than 1.15 million women, about 1% of whom were diagnosed with hyperemesis gravidarum before 22 weeks of gestation.
Women with hyperemesis gravidarum in their first trimester had only a slightly increased risk of pre-eclampsia.
But those experiencing the condition in the second trimester were more than twice as likely to develop preterm pre-eclampsia, more than three times as likely to have a placental abruption and almost 40% more likely to have a small-for-gestational-age child, than women without the condition.
“The finding of a stronger association between hyperemesis gravidarum in the second trimester and preterm pre-eclampsia suggests that hyperemesis gravidarum could be associated with abnormal placentation,” the authors wrote.
Furthermore, women with late-onset hyperemesis gravidarum could have delayed stimulation of thyroxin, which may affect