Anaemia in kidney patients linked to cytomegalovirus

US researchers have married clinical observations with cell culture experiments to show that CMV infection inhibits the ability of cells to produce erythropoietin.

Examination of kidneys in 13 patients with CKD found nine were positive for active CMV infection, and that those with higher levels of anti-CMV antibodies had fewer red blood cells.

The research identified that CMV inhibits the production of the protein, HIF-2α, required for erythropoietin production, thus