Antibiotic effects limited in lungs

Data from a European primary care trial have been analysed to see if these patients benefit from treatment with amoxycillin.

This trial involved patients with acute cough or suspected LRTI. About 15% of the patients had chronic lung disease. After those with suspected pneumonia were excluded, 2061 patients were randomised to take amoxycillin or a placebo three times a day for a week.

Taking the antibiotic made no significant difference to overall severity or duration of symptoms. Patients with green sputum got better slightly faster with amoxycillin.

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