Antidepressants work in IBS

Antidepressants and some psychological therapies are an effective means of treating irritable bowel syndrome, according to a new meta-analysis.

Symptoms improved in 56% of IBS patients on antidepressants compared with only 35% on placebo, data from 16 studies showed.

Results were similar for both tricyclic antidepressants and selective serotonin reuptake inhibitors, found the researchers led by Dr Alex Ford of the Leeds Gastroenterology Institute in the UK.

However adverse events were significantly higher