Antipsychotics first line for mania
Therapeutic Guidelines: Psychotropic advises using antipsychotics to gain rapid control of the patient’s symptoms.
The recommendation is to use olanzapine or risperidone as first-line therapy. They can be effective even if the patient does not have psychotic symptoms.
Other ‘second-generation’ antipsychotics and haloperidol are second-line therapy.
Alternative second choices are lithium, sodium valproate or carbamazepine.
Combinations of drugs are often