‘Apple’ shaped bodies may raise renal disease risk

Among a group of 315 adults with normal BMI and no hypertension or diabetes, central adiposity was associated with lower glomerular filtration rate, lower effective renal plasma flow and higher filtration fraction.

This unfavourable renal profile may underlie the increased risk of developing kidney disease among people with apple-shaped compared to pear-shaped bodies, the researchers said.

They may benefit from interventions such as salt restriction or drug therapy.

J Am Soc Nephrol 2013; online 11 April