Aspirin neuroprotective in elderly women at high CV risk

An observational study of nearly 700 Swedish women aged 70 to 90 years, most of whom had a 10% or higher 10-year Framingham CV risk score, suggested aspirin may damp down inflammation and arrest cognitive decline by enhancing cerebral blood flow through its antiplatelet effects, researchers said.

They found that among the high-risk patients, those taking daily aspirin (75–160mg) over five years actually increased mini-mental state exam scores compared to those who had never taken aspirin.

Among the 66 women who took aspirin daily for five years, cognitive decline was more pronounced