Azithromycin raises risk of CV death

Compared with patients who took amoxycillin, patients who took azithromycin for five days had a “small” but significant increased risk of death – and that risk was much higher among patients with the most cardiovascular risk factors at baseline.

Azithromycin was associated with an extra 47 cardiovascular deaths per million overall, and 245 additional cardiovascular deaths per million among the patients in the highest decile for cardiovascular disease risk.