Benzodiazepines and dementia risk
In September 2014, a case-control study of nearly 9000 older Canadians found that daily use of benzodiazepines for more than three months was associated with increased incidence of Alzheimer’s disease – even after adjusting for anxiety, depression and insomnia.1
As cumulative exposure increased, so did Alzheimer’s incidence, with the highest rates among people who took benzodiazepines for more than six months.1
While the findings cannot prove cause or effect, they do add to the evidence for a link between long-term use of benzodiazepines and dementia.
A 2012 systematic