Better paediatric IBD outcomes with higher infliximab trough levels

Study supports proactive drug management

Higher infliximab trough levels are associated with higher remission rates in children with inflammatory bowel disease (IBD), a retrospective study suggests.

Conversely, low infliximab trough levels appear to correlate with poor clinical outcomes, but the role of therapeutic drug monitoring during infliximab maintenance therapy is poorly studied in paediatric IBD patients.

Dr Severine Vermeire and colleagues from University Hospitals Leuven in Belgium investigated whether infliximab trough levels during maintenance