Brain degeneration seen in elderly with apathy symptoms

Data from more than 4000 people aged 70–80 years in Iceland found those with more than two apathy symptoms had significantly smaller grey matter volume and white matter volume on MRI compared to those with one or no symptoms.

Subjects with apathy were also more likely to have white matter lesions in the frontal lobe independent of depressive symptoms, a finding which has therapeutic implications, the researchers said.

While serotonergic drugs may be effective for relieving depression