Cannabis trial kicks off for knee OA

An Australian trial to test the efficacy of a synthetic cannabis gel in reducing pain in knee osteoarthritis has started recruiting.

The double-blind, placebo-controlled trial will involve 320 patients from Queensland, NSW and Victoria and will use an investigational cannabidiol product marketed by US biotech company Zynerba.

Patients will apply the gel to their shoulders twice daily for 12 weeks, with a primary endpoint of