Caution over SSRI use in infertility and pregnancy

Many infertile women will report depressive symptoms during their treatment and up to 11% could be on SSRIs, the authors said.

“There is minimal evidence that antidepressants provide a significant benefit to women struggling to conceive,” they said. “On the contrary, there is mounting evidence that SSRIs may in fact decrease the pregnancy rates from fertility treatment [and] increase the risk of pregnancy loss.”

The review showed use of SSRIs in pregnancy was associated with an increased risk of miscarriage, early delivery, birth