Child leukaemia linked to maternal coffee drinking

Chinese researchers included seven case control studies involving more than 2000 cases in their review, finding that compared to those never drinking coffee, the risk of childhood leukaemia increased by 22% for low intake of coffee and by 72% for high intake.

Caffeine may act as a topoisomerase II inhibitor, a DNA repair inhibitor or a carcinogen metabolism inhibitor, the researchers said, adding the effect of drinking decaffeinated coffee had been poorly studied.

American Journal of Obstetrics and Gynecology 2013;