Childhood-onset IBD triples mortality rate

Children with ulcerative colitis most at risk

Children diagnosed with inflammatory bowel disease (IBD) have a three-fold increase in mortality compared with the general population when followed into adulthood, a large Swedish study has found.

Although the highest risk was seen in patients with childhood-onset ulcerative colitis (UC), children diagnosed with Crohn's disease and IBD-unclassified also were at elevated risk of death.

Researchers say the mortality increase appeared not to diminish over time, even with the introduction of new drugs for treating IBD, such as immunomodulators and biologics.