Chronic migraine patients receive small benefit from botulinum
1st May 2012
By Staff writer
The treatment is also not associated with greater benefits than placebo in preventing episodic migraines or chronic tension-type headaches, US researchers found after pooling data from 27 randomised trials.
And in comparative effectiveness trials, botulinum toxin A was not superior to valproate, topiramate or amitriptyline, they found.
Compared to placebo, botulinum toxin A was associated with a greater frequency of blepharoptosis, skin tightness, paraesthesias, neck stiffness, muscle weakness and neck pain, the researchers reported.
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