Cognition impaired with depression

The data came from the Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes (ACCORD-MIND) trial in around 3000 type 2 diabetes patients at high risk of cardiovascular events.

It showed that patients with depression at baseline had lower cognitive scores on psychomotor speed, memory and executive functioning after 40 months of follow-up, than those without depression.

The effect of depression on the risk of cognitive decline was unaffected by previous cardiovascular disease, baseline cognition, age, or intensive versus standard glucose