Coming to grips with comedones

IT IS dark on the skin surface and seen in the openings of hair follicles. It is a comedo. Comedones are made up of lining skin cells of the infundibulum or hair follicle opening plus triglycerides in the sebaceous secretion which are converted to fatty acids by the Propionibacterium acnes in the hair follicle. These fatty acids accelerate keratinisation and lead to initially white (closed) comedones and later oxidation of the sebum occurs and black (open) comedones are formed.

Androgens also play a role by accelerating follicular keratinisation. As the