Congenital heart defects linked to pre-eclampsia

Pre-eclampsia has been linked to an increased risk of congenital heart defects in offspring, with early onset of the condition being associated with more serious defects, a Canadian study shows.

Infants of women who developed pre-eclampsia before 34 weeks gestation are more likely to have defects, including tetralogy of Fallot, hypoplastic left heart and coarctation of the aorta, than those whose mothers developed pre-eclampsia later in pregnancy, the study reveals.