Debate over HRT link to colorectal cancer

The WHI study also found that HRT decreased colorectal cancer (CRC) risk, so rates of CRC should have gone up, researchers claim. However, that wasn’t the case, as incidence rates of colorectal cancer dropped by 5.9% even as oestrogen plus progestogen sales plummeted by 63%, contrary to the predictions of the WHI, they said in a recent paper.

However, Australian experts said their study, which involved re-analysis of WHI and comparison of colorectal cancer estimates against incidence in women older than 50 years in a US database, was methodologically flawed.

Clinical Associate Professor Karen Canfell, of