Depression doesn’t mediate smoking therapy response

Researchers looked at outcomes among 1730 smokers receiving treatment at outpatient hospital clinics, including intensive counselling and, for 77% of them, pharmacotherapy.

Overall, 38.7% of smokers without depression were abstinent one year after starting treatment compared to 32.5% of smokers with depression, a non-statistically significant difference.

Further analysis showed a difference between the genders, with male smokers with a history of depression having lower rates of abstinence