Depression linked to rapid decline in CKD

CLINICIANS treating patients with early kidney disease should actively manage symptoms of depression as they may adversely affect outcomes, experts say.

A 10-year US study of more than 5500 people aged 65 years or older found new onset of clinically severe kidney disease or end-stage renal disease was more common in patients with depressive symptoms.

Individuals with chronic kidney disease (CKD) were 20% more likely to experience depression than their counterparts who did not have kidney disease, according to findings from the study, which excluded people on dialysis.

Researchers found 3.9% of the participants were hospitalised with acute kidney injury over the 10 years of follow-up.

People with depressive symptoms were significantly more likely than non-depressed people to be hospitalised with acute kidney injury (5% versus 3.7%), and this was independent of traditional renal disease risk factors, the authors said.