Diabetes drug may help prevent aortic rupture

The cheap diabetes drug metformin may have potential for slowing the growth of abdominal aortic aneurysms, Australian research suggests.

Use of the drug was associated with 40-87% reductions in aneurysm growth in a Queensland observational study of 1700 patients undergoing yearly surveillance for abdominal aortic aneurysms (AAA).

This included 173 patients receiving metformin for diabetes. This group showed signs of slower growth over 1-4 years compared with other patients in the study cohorts.

The findings suggested a potential new role for metformin