Diabetes link to brain ageing and less volume
THE brains of people with diabetes have smaller volumes – equivalent to approximately six years of chronological ageing – compared with the brains of people without diabetes, research shows.
US researchers looked at whether there was a link between markers of diabetes and measures of structural and functional brain ageing.
Among nearly 2500 people from the Framingham Offspring Study, the researchers found that diabetes, fasting insulin, HbA1c levels and insulin resistance were all inversely related to total cerebral brain volume (TCBV).
People with diabetes had a 1.24% lower TCBV than those without diabetes, they said.
Diabetes, HbA1c, insulin resistance and fasting insulin were also related to poorer executive function.
And insulin resistance and fasting insulin, but not diabetes and HbA1c, were inversely associated with visuospatial memory.
“These findings suggest that the insulin-resistant states