Diabetes risk rises with statin potency

The study of nearly 500,000 people aged 66 or older taking statins, who had no history of diabetes, showed that those treated with atorvastatin had a 22% increase in the risk of new onset diabetes, compared with pravastatin.

Pravastatin was used as the comparator because it has been shown to have favourable effects on incident diabetes in animal models and clinical trials.

Similarly, rosuvastatin increased the risk of diabetes by 18% and simvastatin by 10%.

However, low-potency statin fluvastatin was not