Disrupted body clock increases diabetes risk
THE study in 24 healthy adults, whose sleep was restricted for eight days – half with fixed bedtimes and half with misaligned bedtimes – showed that insulin sensitivity went down in both groups with sleep restriction.
However, insulin sensitivity declined by 58% in the group with misaligned sleep, nearly double the 32% decline in those whose sleep was aligned with normal bedtimes.
Similarly, an increased risk of disposition to diabetes, which included insulin sensitivity and β-cell response, was greater after circadian misalignment.
Diabetes 2014; 63:1860-69