Specialist Updates

Drug combo effective in bipolar depression

Lamotrigine in conjunction with quetiapine is effective in treating the acute phase of bipolar depression, say UK researchers.

Their randomised, double-blinded trial of 200 people with bipolar depression found a “statistically and clinically significant” reduction in depressive symptoms with lamotrigine plus quetiapine, compared with placebo plus quetiapine.

The lamotrigine group did better