Drug therapy for treatment of osteoporosis

Consider an anti-osteoporotic drug after a minimal trauma fracture in someone with osteoporosis. An anti-osteoporotic drug reduces the risk of further fracture. Those who are at high risk of minimal trauma fracture because they are ≥70 years and have a BMD T-score ≤–3.0 (primary prevention), or people who are taking a glucocorticoid and meet certain criteria, may also be eligible for an anti-osteoporotic drug. 1

People with a minimal trauma fracture are at increased risk of further fractures: the risk of vertebral fracture is about four times higher in women with a previous vertebral fracture than in those without. 2 Despite this, research has shown less than 30% of Australian postmenopausal women with a previous fracture were taking an anti-osteoporotic drug and only 10% of Australian men who were eligible for a PBS-subsidised bisphosphonate were taking (or had taken) one. 3,4

All anti-osteoporotic drugs reduce fracture risk