E-nose may be able to sniff bowel cancer at the bedside

The proof-of-concept study, conducted at the VU University Medical Center in Amsterdam, used an “e-nose” – a portable array of nanosensors that react to different fractions of volatile organic compounds (VOCs) – to detect a smellprint in stool samples.

The researchers took frozen stool samples from 40 patients with colorectal cancer, 60 patients with advanced adenomas and 57 healthy controls, who were to undergo an endoscopy. They showed that the VOCs from the faecal gas of patients with CRC