Egg allergy resolved with oral immunotherapy
The physicians used egg-white powder in escalated doses to desensitise the children in a placebo-controlled study involving 55 participants aged 5–18 years at multiple sites in the US.
They performed an oral food challenge with egg-white powder and cooked egg at 10 months and again at 22 months after the study began.
Half of the children in the active arm passed the first challenge but none of those given a placebo (cornstarch) passed. Some 75% of children given egg sensitisation passed the second test.
“We found that oral immunotherapy provides protection in a majority of children with egg allergy… and represents a highly promising therapeutic intervention for food allergy,” the authors concluded.
Some 15% of children dropped out of the study, mostly because of allergic