Elevated CRP levels linked to depression

Danish researchers analysed CRP levels using cross-sectional data from two general population studies, which included 73,131 men and women aged 20–100 years.

Increasing CRP levels were associated with increasing risk for psychological distress and depression, as well  as hospitalisation for depression. Risk was greatest when CRP levels exceeded 10mg/L.

The authors suggest future research should examine whether adding anti-inflammatory drugs to antidepressants for treating depression could improve outcomes. 

Arch Gen Psychiatry; online 24 Dec 2012.