Endoscopy fails to catch many coeliac cases

Over ten percent of new cases of coeliac disease are likely to be missed after routine endoscopy, Queensland researchers find.

Their study looked at nearly 2,600 patients presenting for upper endoscopy following mainly gastrointestinal symptoms, with 35 new cases of coeliac disease eventually identified after endoscopy, duodenal biopsy and antibody testing.

However almost a quarter of these cases presented with atypical symptoms and half of them had normal or nearly normal duodenal mucosa, found the authors