Eruption of a pus-filled kind

A 45-YEAR-OLD man presents with striking pus-filled blisters on the palms and soles (Figure 1). There is moderate discomfort and significant impairment to walking and using his hands.

The eruptions started a month ago as small pustules that rapidly coalesced into flaccid pus-filled blisters. He has no history of dermatitis or allergies and is experiencing this eruption for the first time. He is otherwise well, smokes a packet a day, and is not on any regular medications. What is the most likely diagnosis?

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