Etanercept tapering effective in early RA

Early RA patients successfully treated with 50mg etanercept plus methotrexate are most  likely to sustain their remission by continuing the treatment at a lower dose, according to NEJM-published research.

The double-blinded study led by Dr Paul Emery of Leeds University randomised nearly 200 patients in remission after combination therapy to one of three arms: 25mg etanercept plus methotrexate, methotrexate alone or placebo.