Fat gene and hip fracture risk link found: study

Drawing on data on 102 hip fractures among 934 postmenopausal women in the Dubbo Osteoporosis Epidemiology Study, the researchers found some common genotypes doubled the risk of fracture, independent of bone density and BMI.

The authors, from the Garvan Institute of Medical Research, Sydney, estimated that based on the number of carriers of risky genotypes, about 17% of hip fracture cases were attributable to the FTO gene variant.

The new knowledge could improve individual fracture risk prediction, they said.