Fetal DNA testing not yet routine

Answer: Non-invasive prenatal testing for Down syndrome using fetal DNA in maternal blood is clinically useful in high-risk pregnancies but prospective studies are needed before its adoption as a routine clinical diagnostic tool. 

Ultrasound measurement of fetal nuchal translucency in combination with analysis of maternal serum to detect Pregnancy Associated Placental Protein-A (PAPP-A) and free β-hCG is offered for all pregnancies as a matter of choice,1,2