Fighting killer cancer cells one fake sugar sachet at a time

THE artificial sweetener saccharin, once suspected to be a carcinogen, may actually be capable of combating aggressive cancers, scientists have found.

New research, part-funded by the Australian Research Council, shows that saccharin binds to and deactivates carbonic anhydrase IX, a protein that significantly drives the growth and spread of cancers in the breast, lung, liver, kidney, pancreas and brain.

Using x-ray crystallography and packets of Sweet’N Low, researchers found that inhibition of carbonic anhydrase IX