First PSA test advised in mid-40s

The Swedish researchers used data from a case-controlled study in 22,000 men followed for 27 years to determine the best time to start PSA screening.

They found that 44% of prostate cancer deaths that occurred within 25–30 years of screening were in men in the highest 10th of PSA concentrations (≥1.6µg/L) at age 45–49, with the same proportion of deaths in the highest 10th at age 51–55.

However, in men aged 40 in the highest 10th of PSA